The parasite Schistocephalus solidus secretes proteins with putative host manipulation functions.

ABSTRACT:

Background

Manipulative parasites are thought to liberate molecules in their external environment, acting as manipulation factors with biological functions implicated in their host's physiological and behavioural alterations. These manipulation factors are part of a complex mixture called the secretome. While the secretomes of various parasites have been described, there is very little data for a putative manipulative parasite. It is necessary to study the molecular interaction between a manipulative parasite and its host to better understand how such alterations evolve.

Methods

Here, we used proteomics to characterize the secretome of a model cestode with a complex life cycle based on trophic transmission. We studied Schistocephalus solidus during the life stage in which be

SUBMITTER: Berger CS 

PROVIDER: S-EPMC8400842 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature