Intestinal Colonization with <i>Tropheryma whipplei</i>-Clinical and Immunological Implications for HIV Positive Adults in Ghana.

ABSTRACT:

Background

Recent studies demonstrated higher prevalence rates of Tropheryma whipplei (T. whipplei) in HIV positive than in HIV negative subjects. However, associations with the immune status in HIV positive participants were conflicting.

Methods

For this cross-sectional study, stool samples of 906 HIV positive and 98 HIV negative individuals in Ghana were tested for T. whipplei. Additionally, sociodemographic parameters, clinical symptoms, medical drug intake, and laboratory parameters were assessed.

Results

The prevalence of T. whipplei was 5.85% in HIV positive and 2.04% in HIV negative participants. Within the group of HIV positive participants, the prevalence reached 7.18% in patients without co-trimoxazole prophylaxis, 10.26% in subje

SUBMITTER: Eberhardt KA 

PROVIDER: S-EPMC8400997 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature