Three broad classifications of acute respiratory failure etiologies based on regional ventilation and perfusion by electrical impedance tomography: a hypothesis-generating study.

ABSTRACT:

Background

The aim of this study was to validate whether regional ventilation and perfusion data measured by electrical impedance tomography (EIT) with saline bolus could discriminate three broad acute respiratory failure (ARF) etiologies.

Methods

Perfusion image was generated from EIT-based impedance-time curves caused by 10 ml 10% NaCl injection during a respiratory hold. Ventilation image was captured before the breath holding period under regular mechanical ventilation. DeadSpace_%, Shunt_% and VQMatch_% were calculated based on lung perfusion and ventilation images. Ventilation and perfusion maps were divided into four cross-quadrants (lower left and right, upper left and right). Regional distribution defects of each quadrant were scored as

SUBMITTER: He H 

PROVIDER: S-EPMC8401348 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature