Biosensor Based Immunoassay: A New Approach for Serotyping of Toxoplasma gondii.

ABSTRACT: Toxoplasmosis is the most reported parasitic zoonosis in Europe, with implications in human health and in the veterinary field. There is an increasing need to develop serotyping of Toxoplasma gondii (T. gondii) in view of greater sensitivity and efficiency, through the definition of new targets and new methodologies. Nanotechnology is a promising approach, with impact in the development of point-of-care devices. The aim of this work was to develop a simple but highly efficient method for Toxoplasma gondii serotyping based on gold nanoparticles. A simple colorimetric method was developed using gold nanoparticles modified with the synthetic polymorphic peptide derived from GRA6 antigen specific for type II T. gondii. The method of preparation of the gold nanoprobes and the experimental condi

SUBMITTER: Sousa S 

PROVIDER: S-EPMC8401488 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature