Minimal Associations between Short-Term Dietary Intake and Salivary Microbiome Composition.

ABSTRACT:

Background

Increasing evidence points to the esophageal microbiome as an important co-factor in esophageal neoplasia. Esophageal microbiome composition is strongly influenced by the oral microbiome. Salivary microbiome assessment has emerged as a potential non-invasive tool to identify patients at risk for esophageal cancer, but key host and environmental factors that may affect the salivary microbiome have not been well-defined. This study aimed to evaluate the impact of short-term dietary intake on salivary microbiome composition.

Methods

Saliva samples were collected from 69 subjects prior to upper endoscopy who completed the Automated Self-Administered 24-Hour (ASA24) Dietary Assessment. Salivary microbiome composition was determined using 16S rRNA amplicon sequencing.

SUBMITTER: Kim J 

PROVIDER: S-EPMC8401849 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature