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An Indole-Based Fluorescent Chemosensor for Detecting Zn2+ in Aqueous Media and Zebrafish.


ABSTRACT: An indole-based fluorescent chemosensor IH-Sal was synthesized to detect Zn2+. IH-Sal displayed a marked fluorescence increment with Zn2+. The detection limit (0.41 μM) of IH-Sal for Zn2+ was greatly below that suggested by the World Health Organization. IH-Sal can quantify Zn2+ in real water samples. More significantly, IH-Sal could determine and depict the presence of Zn2+ in zebrafish. The detecting mechanism of IH-Sal toward Zn2+ was illustrated by fluorescence and UV-visible spectroscopy, DFT calculations, 1H NMR titration and ESI mass.

SUBMITTER: Choe D 

PROVIDER: S-EPMC8402251 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature

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An Indole-Based Fluorescent Chemosensor for Detecting Zn<sup>2+</sup> in Aqueous Media and Zebrafish.

Choe Donghwan D   So Haeri H   Park Soyoung S   Lee Hangyul H   Chae Ju Byeong JB   Kim Jiwon J   Kim Ki-Tae KT   Kim Cheal C  

Sensors (Basel, Switzerland) 20210819 16


An indole-based fluorescent chemosensor <b>IH-Sal</b> was synthesized to detect Zn<sup>2+</sup>. <b>IH-Sal</b> displayed a marked fluorescence increment with Zn<sup>2+</sup>. The detection limit (0.41 μM) of <b>IH-Sal</b> for Zn<sup>2+</sup> was greatly below that suggested by the World Health Organization. <b>IH-Sal</b> can quantify Zn<sup>2+</sup> in real water samples. More significantly, <b>IH-Sal</b> could determine and depict the presence of Zn<sup>2+</sup> in zebrafish. The detecting mech  ...[more]

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