Do initial concentration and activated sludge seasonality affect pharmaceutical biotransformation rate constants?

ABSTRACT: Pharmaceuticals find their way to the aquatic environment via wastewater treatment plants (WWTPs). Biotransformation plays an important role in mitigating environmental risks; however, a mechanistic understanding of involved processes is limited. The aim of this study was to evaluate potential relationships between first-order biotransformation rate constants (k_b) of nine pharmaceuticals and initial concentration of the selected compounds, and sampling season of the used activated sludge inocula. Four-day bottle experiments were performed with activated sludge from WWTP Groesbeek (The Netherlands) of two different seasons, summer and winter, spiked with two environmentally relevant concentrations (3 and 30 nM) of pharmaceuticals. Concentrations of the compounds were measured by

SUBMITTER: van Bergen TJHM 

PROVIDER: S-EPMC8403117 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature