Association of rs9939609-FTO with metabolic syndrome components among women from Mayan communities of Chiapas, Mexico.

ABSTRACT:

Background

Metabolic syndrome (MetS) is a complex cluster of risk factors, considered as a polygenic and multifactorial entity. The objective of this study was to determine the association of rs9939609-FTO polymorphism and MetS components in adult women of Mayan communities of Chiapas.

Methods

In a cross-sectional study, sociodemographic, anthropometric, clinical, and biochemical data were obtained from 291 adult women from three regions of Chiapas, Mexico. The prevalence of MetS and the allele and genotype frequencies of the rs9939609-FTO were estimated. Multivariate logistic regression models were used to assess the association of the single nucleotide polymorphism (SNP) with each of the MetS components.

Results

The MetS prevalence was 60%. We found a statistically

SUBMITTER: Ortega PEN 

PROVIDER: S-EPMC8403373 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature