Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery; statistical challenges in comparison.

ABSTRACT:

Background

Despite several studies comparing off- and on-pump coronary artery bypass grafting (CABG), the effectiveness and outcomes of off-pump CABG still remain uncertain.

Methods

In this registry-based study, we assessed 8163 patients who underwent isolated CABG between 2014 and 2016. Propensity score matching (PSM), inverse probability of weighting (IPW) and covariate adjustment were performed to correct for and minimize selection bias.

Results

The overall mean age of the patients was 62 years, and 25.7% were women. Patients who underwent off-pump CABG had shorter length of hospitalization (p < 0.001), intubation time (p = 0.003) and length of ICU admission (p < 0.001). Off-pump CABG was associated with higher risk of 30-days mortality (OR: 1.7; 95% CI 1.09-2.65;

SUBMITTER: Sheikhy A 

PROVIDER: S-EPMC8403445 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature