Urinary arsenic and heart disease mortality in NHANES 2003-2014.

ABSTRACT:

Background

Evidence evaluating the prospective association between low-to moderate-inorganic arsenic (iAs) exposure and cardiovascular disease in the general US population is limited. We evaluated the association between urinary arsenic concentrations in National Health and Nutrition Examination Survey (NHANES) 2003-2014 and heart disease mortality linked from the National Death Index through 2015.

Methods

We modeled iAs exposure as urinary total arsenic and dimethylarsinate among participants with low seafood intake, based on low arsenobetaine levels (N = 4990). We estimated multivariable adjusted hazard ratios (HRs) for heart disease mortality per interquartile range (IQR) increase in urinary arsenic levels using survey-weighted, Cox proportional hazards models, and evalua

SUBMITTER: Nigra AE 

PROVIDER: S-EPMC8403626 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature