Nuclear androgen and progestin receptors inversely affect aggression and social dominance in male zebrafish (Danio rerio).

ABSTRACT: Aggression is a fundamental behavior displayed universally among animal species, but hyper- or hypo-aggressiveness can be maladaptive with negative consequences for individuals and group members. While the social and ecological significance of aggression is well understood, the specific neurobiological and hormonal mechanisms responsible for mediating aggression have not been fully elucidated. Previous studies have shown a relationship between aggressive acts and circulating gonadal steroids, but whether classical nuclear steroid receptors regulate aggression in animals is still uncertain. We examined whether the nuclear androgen receptor (Ar) and nuclear progestin receptor (Pgr) were necessary for aggressive behaviors and maintenance of a dominance relationship in male zebrafish (Danio re

SUBMITTER: Carver JJ 

PROVIDER: S-EPMC8403641 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature