Functional connectivity of spoken language processing in early-stage Parkinson's disease: An MEG study.

ABSTRACT: Parkinson's disease (PD) is a neurodegenerative disorder, well-known for its motor symptoms; however, it also adversely affects cognitive functions, including language, a highly important human ability. PD pathology is associated, even in the early stage of the disease, with alterations in the functional connectivity within cortico-subcortical circuitry of the basal ganglia as well as within cortical networks. Here, we investigated functional cortical connectivity related to spoken language processing in early-stage PD patients. We employed a patient-friendly passive attention-free paradigm to probe neurophysiological correlates of language processing in PD patients without confounds related to active attention and overt motor responses. MEG data were recorded from a group of newly diagnos

SUBMITTER: Hyder R 

PROVIDER: S-EPMC8403765 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature