Parallel hippocampal-parietal circuits for self- and goal-oriented processing.

ABSTRACT: The hippocampus is critically important for a diverse range of cognitive processes, such as episodic memory, prospective memory, affective processing, and spatial navigation. Using individual-specific precision functional mapping of resting-state functional MRI data, we found the anterior hippocampus (head and body) to be preferentially functionally connected to the default mode network (DMN), as expected. The hippocampal tail, however, was strongly preferentially functionally connected to the parietal memory network (PMN), which supports goal-oriented cognition and stimulus recognition. This anterior-posterior dichotomy of resting-state functional connectivity was well-matched by differences in task deactivations and anatomical segmentations of the hippocampus. Task deactivations were loc

SUBMITTER: Zheng A 

PROVIDER: S-EPMC8403906 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature