Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel.

ABSTRACT:

Background

Countries across the globe have mobilized their armed forces in response to COVID-19, placing them at increased risk for viral exposure. Humoral responses to SARS-CoV-2 among military personnel serve as biomarkers of infection and provide a basis for disease surveillance and recognition of work-related risk factors.

Methods

Enzyme-linked immunosorbent assays (ELISA) were used to measure SARS-CoV-2 spike antigen-specific IgG in serum obtained from N = 988 US National Guard soldiers between April-June 2020. Occupational information, e.g. military operating specialty (MOS) codes, and demographic data were obtained via questionnaire. Plaque assays with live SARS-CoV-2 were used to assess serum neutralizing capacity for limited subjects (N = 12).

Results

The SAR

SUBMITTER: Zell J 

PROVIDER: S-EPMC8405017 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature