Effects of Exercise and Weight Loss on Proximal Aortic Stiffness in Older Adults With Obesity.

ABSTRACT:

Background

Obesity may accelerate age-related increases in aortic stiffness. Although aerobic exercise training generally has favorable effects on aortic structure and function, exercise alone may not be sufficient to improve aortic stiffness in older adults with obesity. We determined the effects of aerobic exercise training with and without moderate- to high-caloric restriction (CR) on the structure and function of the proximal aorta in 160 older (65-79 years) men and women with obesity (body mass index=30-45 kg/m²).

Methods

Participants were randomly assigned to 1 of 3 groups: aerobic exercise training only (treadmill 4 days/week for 30 minutes at 65% to 70% of heart rate reserve; n=56), aerobic exercise training plus moderate CR (n=55), or aerobic exercise tra

SUBMITTER: Brinkley TE 

PROVIDER: S-EPMC8405553 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature