Searching for treatments for non-G12C-KRAS mutant cancers.
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ABSTRACT:
SUBMITTER: Guo C
PROVIDER: S-EPMC8405631 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Searching for treatments for non-G12C-KRAS mutant cancers.
Guo Christina C Banerji Udai U
British journal of cancer 20210415 5
KRAS mutations drive a wide variety of cancers. Drugs targeting the protein product of KRAS<sup>G12C</sup> mutations are currently being evaluated show preliminary efficacy in clinical trials. A clinical trial of VS-6766, a dual RAF-MEK inhibitor, has reported early single agent activity in non-G12C mutated KRAS driven cancers. ...[more]
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