Improvement in vitamin B₁₂ status of Wistar rats by supplementing the diet with Chlorella vulgaris biomass.

ABSTRACT: The sources of bioavailable vitamin B₁₂ are limited, and most of them are animal-derived. Chlorella vulgaris, a freshwater microalga, is known for immune system boosting, nutraceutical properties and presence of a natural form of vitamin B₁₂. The present study focused on the in vivo evaluation of the Chlorella biomass as a source of bioavailable vitamin B₁₂ to alleviate the vitamin B₁₂ deficiency status of Wistar rats. Experimental animals were evaluated for the vitamin B₁₂ deficiency-related circulatory marker (serum vitamin B₁₂) and functional markers (plasma homocysteine and urinary methylmalonic acid), haematological and histological changes. The results showed that an increase of 2.4-fold in urinary methyl

SUBMITTER: Madhubalaji CK 

PROVIDER: S-EPMC8405763 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature