Central functional reorganization and recovery following facial-hypoglossal neurorrhaphy for facial paralysis.

ABSTRACT:

Objective

Functional deficits induced by nerve injuries can be restored by achieving effective reinnervation of the denervated targets and functional reorganization of the central nervous system after nerve reconstruction. In this study, we investigated the effect and extent of cortical functional reorganization related to the ability of transferred hypoglossal neurons to restore facial function in facial paralysis patients after a surgical bridge of neurorrhaphy ectopically between the ipsilateral hypoglossal nerve and injured facial nerve.

Methods

We treated 23 patients (35.4 ± 10.3 years, 10 males) and followed them up for 2.9 ± 0.61 years. We used motor-task-related functional magnetic resonance imaging to map activation change at multiple time points before and after ne

SUBMITTER: Ling M 

PROVIDER: S-EPMC8405913 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature