Denoising and Multiple Tissue Compartment Visualization of Multi-b-Valued Breast Diffusion MRI.

ABSTRACT:

Background

Multi-b-valued/multi-shell diffusion provides potentially valuable metrics in breast MRI but suffers from low signal-to-noise ratio and has potentially long scan times.

Purpose

To investigate the effects of model-based denoising with no loss of spatial resolution on multi-shell breast diffusion MRI; to determine the effects of downsampling on multi-shell diffusion; and to quantify these effects in multi-b-valued (three directions per b-value) acquisitions.

Study type

Prospective ("fully-sampled" multi-shell) and retrospective longitudinal (multi-b).

Subjects

One normal subject (multi-shell) and 10 breast cancer subjects imaging at four timepoints (multi-b).

Field strength/sequence

3T multi-shell acquisition and 1.5T multi-b acquisition.

Ass

SUBMITTER: Tan ET 

PROVIDER: S-EPMC8406040 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature