Renoprotective role of bariatric surgery in patients with established chronic kidney disease.

ABSTRACT:

Background

Bariatric surgery (BS) has been postulated as the most effective measure for weight reduction. Weight loss improves metabolic parameters and exerts changes in renal function that lead to the amelioration of absolute or relative glomerular hyperfiltration, a condition that may be renoprotective in the long term. However, few studies have demonstrated the influence of BS in patients with severe obesity and chronic kidney disease (CKD). Our objective was to analyse the evolution of renal function, adipose tissue-derived molecules and inflammatory parameters in patients with CKD after BS.

Methods

This is an observational and prospective study. Thirty patients were screened and 12 were included between January 2016 and January 2018 with a 24-month follow-up. Glomerular

SUBMITTER: Morales E 

PROVIDER: S-EPMC8406062 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature