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Serum phosphorus and calcium levels, and kidney disease progression in immunoglobulin A nephropathy.


ABSTRACT:

Background

Disorders of calcium and phosphorus metabolism have been reported to be associated with all-cause and cardiovascular mortality in patients requiring long-term dialysis therapy. However, its role in disease progression is not well established in patients without dialysis, especially in immunoglobulin A (IgA) nephropathy. We aim to evaluate the association of serum phosphorus and calcium and progression of IgA nephropathy.

Methods

We assessed 2567 patients with IgA nephropathy at the First Affiliated Hospital, College of Medicine, Zhejiang University. Serum phosphorus and calcium were collected at the time of kidney biopsy and at each visit. The associations of serum phosphorus and serum calcium with composite kidney disease progression events, defined as 50% estima

SUBMITTER: Yu G 

PROVIDER: S-EPMC8406074 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature