The DELUX study: development of lung volumes during extubation of preterm infants.

ABSTRACT:

Objective

To measure changes in end-expiratory lung impedance (EELI) as a marker of functional residual capacity (FRC) during the entire extubation procedure of very preterm infants.

Methods

Prospective observational study in preterm infants born at 26-32 weeks gestation being extubated to non-invasive respiratory support. Changes in EELI and cardiorespiratory parameters (heart rate, oxygen saturation) were recorded at pre-specified events during the extubation procedure compared to baseline (before first handling of the infant).

Results

Overall, 2912 breaths were analysed in 12 infants. There was a global change in EELI during the extubation procedure (p = 0.029). EELI was lowest at the time of extubation [median (IQR) difference to baseline: -0.30 AU/kg (-0.46; -0.1

SUBMITTER: Plastina L 

PROVIDER: S-EPMC8406659 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature