Visual Impairments Are Associated With Retinal Microvascular Density in Patients With Parkinson's Disease.

ABSTRACT:

Objective

This study aimed to evaluate retinal microvascular density in patients with Parkinson's disease (PD) and its correlation with visual impairment.

Methods

This cross-sectional study included 24 eyes of 24 patients with PD and 23 eyes of 23 healthy controls. All participants underwent ophthalmic examination, visual evoked potential (VEP) test, 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), and optical coherence tomography angiography (OCTA) examination. The correlation between retinal microvascular density and visual parameter was evaluated using Spearman correlation analysis, and the area under receiver operating characteristic curve (AUROC) was calculated.

Results

Parkinson's disease patients had prolonged P100 latency (P =

SUBMITTER: Zhou M 

PROVIDER: S-EPMC8406760 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature