Accelerated osteoarthritis in women with polycystic ovary syndrome: a prospective nationwide registry-based cohort study.

ABSTRACT:

Background

Osteoarthritis (OA) is the most common form of arthritis with multiple risk factors implicated including female sex and obesity. Metabolic dysregulation associated with obesity leading to metabolic syndrome is a proposed component of that association. Polycystic ovary syndrome (PCOS) commonly affects women of reproductive age and these women are at higher risk of developing metabolic syndrome and thus likely to represent a high-risk group for early OA development. There are no published studies exploring the epidemiology of knee, hip and hand OA in women diagnosed with PCOS.

Study aim

To assess the prevalence and incidence of knee, hip and hand osteoarthritis (OA) in women with polycystic ovary syndrome (PCOS) when compared with age-matched controls.

Methods

SUBMITTER: Kluzek S 

PROVIDER: S-EPMC8406767 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature