Impact of very preterm birth and post-discharge growth on cardiometabolic outcomes at school age: a retrospective cohort study.

ABSTRACT:

Background

Adverse metabolic outcomes later in life have been reported among children or young adults who were born as preterm infants. This study was conducted to examine the impact of very preterm/very low birth weight (VP/VLBW) birth and subsequent growth after hospital discharge on cardiometabolic outcomes such as insulin resistance, fasting glucose, and systolic and diastolic blood pressure (BP) among children at 6-8 years of age.

Methods

This retrospective cohort study included children aged 6-8 years and compared those who were born at < 32 weeks of gestation or weighing < 1,500 g at birth (n = 60) with those born at term (n = 110). Body size, fat mass, BP, glucose, insulin, leptin, adiponectin, and lipid profiles were measured. Weight-for-age z-score changes between

SUBMITTER: Yun J 

PROVIDER: S-EPMC8406828 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature