Grip strength from midlife as an indicator of later-life brain health and cognition: evidence from a British birth cohort.

ABSTRACT:

Background

Grip strength is an indicator of physical function with potential predictive value for health in ageing populations. We assessed whether trends in grip strength from midlife predicted later-life brain health and cognition.

Methods

446 participants in an ongoing British birth cohort study, the National Survey of Health and Development (NSHD), had their maximum grip strength measured at ages 53, 60-64, and 69, and subsequently underwent neuroimaging as part of a neuroscience sub-study, referred to as "Insight 46", at age 69-71. A group-based trajectory model identified latent groups of individuals in the whole NSHD cohort with below- or above-average grip strength over time, plus a reference group. Group assignment, plus standardised grip strength levels and change

SUBMITTER: Dercon Q 

PROVIDER: S-EPMC8406895 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature