Prognosis of Incidental Brain Metastases in Patients With Advanced Renal Cell Carcinoma.

ABSTRACT:

Background

Metastatic renal cell carcinoma (mRCC) management guidelines recommend brain imaging if clinically indicated and the rate of occult central nervous system (CNS) metastasis is not well-defined. Early detection could have major therapeutic implications, because timely interventions may limit morbidity and mortality.

Patients and methods

A retrospective review was performed to characterize patients with mRCC incidentally diagnosed with asymptomatic brain metastases during screening for clinical trial participation at Gustave Roussy and Memorial Sloan Kettering Cancer Center. Descriptive statistics and time-to-event methods were used to evaluate the cohort.

Results

Across 68 clinical trials conducted between 2001 and 2019 with a median 14.1-month follow-up, 72

SUBMITTER: Kotecha RR 

PROVIDER: S-EPMC8407454 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature