VB-Ea-5: a lytic bacteriophage against multi-drug-resistant Enterobacter aerogenes.

ABSTRACT:

Background and objectives

Multi-drug-resistant Enterobacter aerogenes is associated with various infectious diseases that cannot be easily treated by antibiotics. However, bacteriophages have potential therapeutic applications in the control of multi-drug-resistant bacteria. In this study, we aimed to isolate and characterize of a lytic bacteriophage that can lyse specifically the multi-drug-resistant (MDR) E. aerogenes.

Materials and methods

Lytic bacteriophage was isolated from Qaem hospital wastewater and characterized morphologically and genetically. Next-generation sequencing was used to complete genome analysis of the isolated bacteriophage.

Results

Based on the transmission electron microscopy feature, the isolated bacteriophage (vB-Ea-5) belongs

SUBMITTER: Habibinava F 

PROVIDER: S-EPMC8408028 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature