The Expression of NRIP1 and LCOR in Endometrioid Endometrial Cancer.

ABSTRACT:

Background

The aim of the study was to analyze the expression of nuclear receptor interacting protein 1 (NRIP1) and its partner ligand-dependent nuclear receptor co-repressor (LCOR) in endometrioid endometrial cancer and to investigate their association with estrogen receptor (ER), progesterone receptor (PR), Ki-67, clinicopathological parameters and patient survival.

Materials and methods

Immunohistochemical evaluation was carried out to investigate the subcellular expression of NRIP1 and LCOR in endometrioid endometrial cancer samples. Statistical analysis was used to identify the correlations of NRIP1 and LCOR expression with clinicopathological variables and to estimate the survival rates.

Results

Endometrial cancer tissues exhibited higher expression of NRIP1 and

SUBMITTER: Flindris S 

PROVIDER: S-EPMC8408693 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature