Comparing success rates in central venous catheter salvage for catheter-related bloodstream infections in adult patients on home parenteral nutrition: a systematic review and meta-analysis.

ABSTRACT:

Background

Catheter-related bloodstream infection (CRBSI) is a life-threatening complication of parenteral nutrition. Therefore, optimal management, ideally with catheter salvage, is required to maintain long-term venous access.

Objectives

We aimed to evaluate successful catheter salvage rates in patients on home parenteral nutrition (HPN).

Methods

Studies were retrieved from medical databases, conference proceedings, and article reference lists. Data were collected relating to clinical outcomes of 3 treatments: systemic antibiotics, antimicrobial lock therapy (ALT), and catheter exchange. ORs and 95% CIs were calculated from a mixed logistic effects model.

Results

From 10,036 identified publications, 28 met the inclusion criteria (22 cohort studies, 5 case-con

SUBMITTER: Gompelman M 

PROVIDER: S-EPMC8408872 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature