Modeling Optimal Laboratory Testing Strategies for Bacterial Meningitis Surveillance in Africa.

ABSTRACT: Since 2010, the introduction of an effective serogroup A meningococcal conjugate vaccine has led to the near-elimination of invasive Neisseria meningitidis serogroup A disease in Africa's meningitis belt. However, a significant burden of disease and epidemics due to other bacterial meningitis pathogens remain in the region. High-quality surveillance data with laboratory confirmation is important to monitor circulating bacterial meningitis pathogens and design appropriate interventions, but complete testing of all reported cases is often infeasible. Here, we use case-based surveillance data from 5 countries in the meningitis belt to determine how accurately estimates of the distribution of causative pathogens would represent the true distribution under different laboratory testing strategie

SUBMITTER: Walker J 

PROVIDER: S-EPMC8409536 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature