The interplay between vaccination and social distancing strategies affects COVID19 population-level outcomes.

ABSTRACT: Social distancing is an effective population-level mitigation strategy to prevent COVID19 propagation but it does not reduce the number of susceptible individuals and bears severe social consequences-a dire situation that can be overcome with the recently developed vaccines. Although a combination of these interventions should provide greater benefits than their isolated deployment, a mechanistic understanding of the interplay between them is missing. To tackle this challenge we developed an age-structured deterministic model in which vaccines are deployed during the pandemic to individuals who do not show symptoms. The model allows for flexible and dynamic prioritization strategies with shifts between target groups. We find a strong interaction between social distancing and vaccination in

SUBMITTER: Guerstein S 

PROVIDER: S-EPMC8409608 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature