A North American prospective study of depression, psychotropic medication use, and semen quality.

ABSTRACT:

Objective

To evaluate the associations of a history of diagnosed depression, current depressive symptoms, and recent use of psychotropic medications with semen quality and to consider mediation of the association between depression and semen quality by medication use.

Design

Prospective cohort study.

Setting

United States.

Patient(s)

The patients were 329 men aged ≥21 years (566 semen samples) who participated in a semen-testing substudy of Pregnancy Study Online. Pregnancy Study Online is an ongoing, web-based preconception cohort study of couples attempting to conceive. At baseline, participants reported information about depression diagnosis, depressive symptoms using the Major Depression Inventory, medication use in the last 4 weeks, and selected covariates

SUBMITTER: Yland JJ 

PROVIDER: S-EPMC8410630 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature