Associations of adverse childhood experiences with stress physiology and insulin resistance in adolescents at risk for adult obesity.

ABSTRACT: Adverse childhood experiences (ACEs) heighten the risk for adult obesity and cardiometabolic disease, but physiological factors underlying this connection are not well understood. We determined if ACEs were associated with physiological stress response and insulin resistance in adolescents at risk for adult obesity. Participants were 90 adolescents 12.0-17.5 years (50% female, 30% Hispanic/Latinx), at risk for adult obesity by virtue of above-average body mass index (BMI; kg/m² ≥ 70th percentile) or parental obesity (BMI ≥ 30 kg/m² ). ACEs were determined as presence (vs. absence) based upon the Schedule for Affective Disorders and Schizophrenia for School-Aged Children. Physiological stress response was measured as heart rate/blood pressure response to the Trier Soci

SUBMITTER: Jimenez V 

PROVIDER: S-EPMC8410633 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature