Population Attributable Risks of Subtypes of Esophageal and Gastric Cancers in the United States.

ABSTRACT:

Introduction

To help target preventive strategies, we estimated US population attributable risks (PARs) of demographic and potentially modifiable risk factors for esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA), and gastric noncardia adenocarcinoma (GNCA).

Methods

We prospectively examined the associations for risk factors and these cancers in 490,605 people in the National Institutes of Health-the American Association of Retired Persons Diet and Health cohort Diet and Health Study cohort from 1995 to 2011. Exposures were obtained from the baseline questionnaire. Diagnoses of gastroesophageal reflux disease were extracted for a subset of eligible National Institutes of Health-the American Association of Retired

SUBMITTER: Wang SM 

PROVIDER: S-EPMC8410651 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature