Physiological MRI Biomarkers in the Differentiation Between Glioblastomas and Solitary Brain Metastases.

ABSTRACT:

Purpose

Glioblastomas (GB) and solitary brain metastases (BM) are the most common brain tumors in adults. GB and BM may appear similar in conventional magnetic resonance imaging (cMRI). Their management strategies, however, are quite different with significant consequences on clinical outcome. The aim of this study was to evaluate the usefulness of a previously presented physiological MRI approach scoping to obtain quantitative information about microvascular architecture and perfusion, neovascularization activity, and oxygen metabolism to differentiate GB from BM.

Procedures

Thirty-three consecutive patients with newly diagnosed, untreated, and histopathologically confirmed GB or BM were preoperatively examined with our physiological MRI approach as part of the cMRI protoco

SUBMITTER: Heynold E 

PROVIDER: S-EPMC8410731 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature