Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior.
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ABSTRACT:
SUBMITTER: Parikh R
PROVIDER: S-EPMC8411113 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Publications
Skin exposure to UVB light induces a skin-brain-gonad axis and sexual behavior.
Parikh Roma R Sorek Eschar E Parikh Shivang S Michael Keren K Bikovski Lior L Tshori Sagi S Shefer Galit G Mingelgreen Shira S Zornitzki Taiba T Knobler Hilla H Chodick Gabriel G Mardamshina Mariya M Boonman Arjan A Kronfeld-Schor Noga N Bar-Joseph Hadas H Ben-Yosef Dalit D Amir Hadar H Pavlovsky Mor M Matz Hagit H Ben-Dov Tom T Golan Tamar T Nizri Eran E Liber Daphna D Liel Yair Y Brenner Ronen R Gepner Yftach Y Karnieli-Miller Orit O Hemi Rina R Shalgi Ruth R Kimchi Tali T Percik Ruth R Weller Aron A Levy Carmit C
Cell reports 20210801 8
Ultraviolet (UV) light affects endocrinological and behavioral aspects of sexuality via an unknown mechanism. Here we discover that ultraviolet B (UVB) exposure enhances the levels of sex-steroid hormones and sexual behavior, which are mediated by the skin. In female mice, UVB exposure increases hypothalamus-pituitary-gonadal axis hormone levels, resulting in larger ovaries; extends estrus days; and increases anti-Mullerian hormone (AMH) expression. UVB exposure also enhances the sexual responsi ...[more]
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