Development and Validation of a Modified Pathologic Nodal Classification System for Cutaneous Melanoma.

ABSTRACT:

Importance

Given the evolving patterns of lymph node evaluation for cutaneous melanoma, it is unclear whether the current nodal classification system will continue to accurately reflect prognosis in the modern era. Existing nodal staging for cutaneous melanoma was developed primarily for patients undergoing completion lymph node dissection (CLND) for node-positive disease and does not produce groups with continuously increasing mortality.

Objective

To develop and validate a modified nodal classification system for cutaneous melanoma.

Design, setting, and participants

This retrospective cohort analysis included 105 785 patients with cutaneous melanoma undergoing surgery and nodal evaluation from January 1, 2004, to December 31, 2015, in the National Cancer Database. Ex

SUBMITTER: Nguyen AT 

PROVIDER: S-EPMC8411360 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature