Patterns of Atopic Eczema Disease Activity From Birth Through Midlife in 2 British Birth Cohorts.

ABSTRACT:

Importance

Atopic eczema is characterized by a heterogenous waxing and waning course, with variable age of onset and persistence of symptoms. Distinct patterns of disease activity such as early-onset/resolving and persistent disease have been identified throughout childhood; little is known about patterns into adulthood.

Objective

This study aimed to identify subtypes of atopic eczema based on patterns of disease activity through mid-adulthood, to examine whether early life risk factors and participant characteristics are associated with these subtypes, and to determine whether subtypes are associated with other atopic diseases and general health in mid-adulthood.

Design, setting, and participants

This study evaluated members of 2 population-based birth cohorts, the 1

SUBMITTER: Abuabara K 

PROVIDER: S-EPMC8411362 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature