Long-Wavelength-Filtered Light Transiently Inhibits Negative Lens-Induced Axial Eye Growth in the Chick Myopia Model.

ABSTRACT:

Purpose

Eye growth and myopia development in chicks, and some other animal models, can be suppressed by rearing under near-monochromatic, short-wavelength blue light. We aimed to determine whether similar effects could be achieved using glass filters that transmit a broader range of short and middle wavelengths.

Methods

On day 6 or 7 post-hatch, 169 chicks were assigned to one of three monocular lens conditions (-10 D, +10 D, plano) and reared for 7 or 10 days under one of four 201-lux lighting conditions: (1) B410 long-wavelength-filtered light, (2) B460 long-wavelength-filtered light, (3) Y48 short-wavelength-filtered light, or (4) HA50 broadband light.

Results

At 7 days, B410 (but not B460) long-wavelength-filtered light had significantly inhibited negative lens in

SUBMITTER: Riddell N 

PROVIDER: S-EPMC8411858 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature