IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature.
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ABSTRACT:
SUBMITTER: Chang EK
PROVIDER: S-EPMC8412065 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
IDH-mutant brainstem gliomas in adolescent and young adult patients: Report of three cases and review of the literature.
Chang Ellen K EK Smith-Cohn Matthew A MA Tamrazi Benita B Ji Jianling J Krieger Mark M Holdhoff Matthias M Eberhart Charles G CG Margol Ashley S AS Cotter Jennifer A JA
Brain pathology (Zurich, Switzerland) 20210507 4
Isocitrate dehydrogenase (IDH) mutations are rare in pediatric and adolescent gliomas. We recently identified three adolescent/young adult (AYA) patients with IDH-mutant low grade gliomas of the brainstem with several key clinicopathologic and molecular features in common. We discuss these three cases and review the current literature. ...[more]
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