Quantitative Point-of-Care Colorimetric Assay Modeling Using a Handheld Colorimeter.

ABSTRACT: Colorimetric assays typically offer a rapid and convenient method to assess analytes that span healthcare monitoring to water quality testing. However, such tests can only provide qualitative results when employed in resource-limited settings or require bulky and expensive equipment such as lab spectrophotometers to allow quantitative measurements. In this paper, we report on the use of a handheld colorimeter to quantitatively determine the concentration of analytes in a manner that is independent of ambient lighting or initial sample color. The method combines the response of the sensor with first-principles modeling that better describes the nature of the assay compared to linear-in-parameters regression modeling that is typically performed in other studies. This method was successfully

SUBMITTER: Abels K 

PROVIDER: S-EPMC8412955 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature