The real-life impact of vaccination on COVID-19 mortality in Europe and Israel.

ABSTRACT:

Objectives

This study aimed at estimating the real-life impact of vaccination on COVID-19 mortality, with adjustment for SARS-CoV-2 variants spread and other factors across Europe and Israel.

Study design

Time series analysis.

Methods

Time series analysis of the daily number of COVID-19 deaths was performed using non-linear Poisson mixed regression models. Variables such as variants' frequency, demographics, climate, health, and mobility characteristics of thirty-two countries between January 2020 and April 2021 were considered as potentially relevant adjustment factors.

Results

The analysis revealed that vaccination efficacy in terms of protection against deaths was 72%, with a lower reduction of the number of deaths for B.1.1.7 vs non-B.1.1.7 variants (70% an

SUBMITTER: Jablonska K 

PROVIDER: S-EPMC8413007 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature