Huntington's disease among immigrant groups and Swedish-born individuals: a cohort study of all adults 18 years of age and older in Sweden.

ABSTRACT:

Background

There is a lack of studies of Huntington's disease (HD) in immigrants.

Objective

To study the association between country of birth and incident HD in first-generation immigrants versus Swedish-born individuals and in second-generation immigrants versus Swedish-born individuals with Swedish-born parents.

Methods

Study populations included all adults aged 18 years and older in Sweden, i.e., in the first-generation study 6,042,891 individuals with 1034 HD cases and in the second-generation study 4,860,469 individuals with 1001 cases. HD was defined as having at least one registered diagnosis of HD in the National Patient Register. The incidence of HD in different first-generation immigrant groups versus Swedish-born individuals was assessed by Cox regression,

SUBMITTER: Wandell P 

PROVIDER: S-EPMC8413185 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature