Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults.

ABSTRACT: Absolute risks of stroke are typically estimated using measurements of cardiovascular disease risk factors recorded at a single visit. However, the comparative utility of single versus sequential risk factor measurements for stroke prediction is unclear. Risk factors were recorded on three separate visits on 13,753 individuals in the prospective China Kadoorie Biobank. All participants were stroke-free at baseline (2004-2008), first resurvey (2008), and second resurvey (2013-2014), and were followed-up for incident cases of first stroke in the 3 years following the second resurvey. To reflect the models currently used in clinical practice, sex-specific Cox models were developed to estimate 3-year risks of stroke using single measurements recorded at second resurvey and were retrospectively

SUBMITTER: Chun M 

PROVIDER: S-EPMC8413314 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature