Relationship between intelligence quotient measures and computerized neurocognitive performance in 22q11.2 deletion syndrome.

ABSTRACT: Intelligence quotient (IQ) testing is standard for evaluating cognitive abilities in genomic studies but requires professional expertise in administration and interpretation, and IQ scores do not translate into insights on implicated brain systems that can link genes to behavior. Individuals with 22q11.2 deletion syndrome (22q11.2DS) often undergo IQ testing to address special needs, but access to testing in resource-limited settings is challenging. The brief Penn Computerized Neurocognitive Battery (CNB) provides measures of cognitive abilities related to brain systems and can screen for cognitive dysfunction. To examine the relation between CNB measures and IQ, we evaluated participants with the 22q11.2DS from Philadelphia and Tel Aviv (N = 117; 52 females; mean age 18.8) who performed b

SUBMITTER: Gur RC 

PROVIDER: S-EPMC8413730 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature