Association between diabetes mellitus and risk of Parkinson's disease: A prisma-compliant meta-analysis.

ABSTRACT:

Background

Previous studies showed inconsistent results regarding associations between diabetes mellitus (DM) and risk of Parkinson's disease (PD). The study aimed to make a meta-analysis to clarify whether DM is a risk factor for PD.

Methods

We searched for articles regarding the effect of DM on risk of PD and published before July 2020 with search terms as follows: ("diabetes mellitus" OR "diabetes") AND ("Parkinson's disease" OR "PD") in the following databases: PubMed, Web of Science, MEDLINE, EMBASE, and Google Scholar. We used STATA 12.0 software to compute multivariate odds ratio (OR) or relative risk (RR) and 95% confidence intervals (CI) regarding the association between DM and risk of PD.

Results

The present study finally included 7 case-control studies (inc

SUBMITTER: Liu W 

PROVIDER: S-EPMC8413776 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature