Utility of FDG PET/CT in assessing bowel inflammation.

ABSTRACT:

Purpose

To develop a methodology for the quantification of gastrointestinal (GI) inflammation as indicated by 2-deoxy-2-(¹⁸F)fluoro-D-glucose (FDG) uptake on positron-emissions tomography/computed tomography (PET/CT) imaging. This is intended to investigate the feasibility of using standard uptake value (SUV) levels to assess levels of GI inflammation in humans.

Methods

131 participants were injected with a weight-controlled dose of FDG 180 minutes prior to PET/CT scanning. Operator-guided software was used to segment the GI tract and perform (SUV) calculations. Regions of interest (ROIs) were created using CT images and stacked to create three dimensional volumes of interest (VOIs). These VOIs defined 6 sections of the GI tract: esophagus, stomach, descending col

SUBMITTER: Gelston D 

PROVIDER: S-EPMC8414397 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature