Delivery Mode Affects Intestinal Microbial Composition and the Development of Intestinal Epithelial Cells.

ABSTRACT:

Background

The infant's intestine contains diverse microbiota, which play an important role in an infant's health.

Objective

This study aimed to analyze the different intestinal microbiota and their function in two delivery modes [vaginal delivery and cesarean section (C-section)] and to investigate the proprieties of bacteria associated with vaginal delivery on the development of intestinal epithelial cells in rat pups.

Materials and methods

We evaluated the intestinal microbial diversity of the stool samples of 51 infants of subjects who underwent vaginal delivery and C-section by sequencing the V4 regions of the 16S rRNA gene and predicted the function of the microbiotas. The infant stool microbiota in the vaginal delivery group was associated with the digestive sy

SUBMITTER: Lyu L 

PROVIDER: S-EPMC8414977 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature