Prediction of Clinical Outcomes With EEG Microstate in Patients With Major Depressive Disorder.

ABSTRACT: Background: The difficulty in timely evaluating patient response to antidepressants has brought great challenge to the treatment of major depressive disorder (MDD). Some studies found that the electroencephalogram (EEG) microstates might be a reliable marker to evaluate patient response to treatment. The present study aims to evaluate the relationship between EEG microstate parameters and MDD symptoms before and after treatment to identify predictive biological markers for patient response. Methods: Thirty drug-naïve MDD patients (20 females and 10 males) were enrolled in this study. All the patients received effective dosages of selective serotonin reuptake inhibitors, and EEG recordings were collected at baseline and 2 weeks of treatment. Brain activities during the eyes-cl

SUBMITTER: Yan D 

PROVIDER: S-EPMC8415359 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature